Description

2-Methoxyphenol-3,4,5,6-D4,Od is a deuterium-labeled isotopologue of guaiacol, a naturally occurring phenolic compound. This stable isotope-labeled standard is essential for ensuring accuracy and reliability in quantitative analytical methods, particularly mass spectrometry. It is primarily used by researchers and quality control laboratories in the pharmaceutical, flavor & fragrance, and environmental analysis sectors for use as an internal standard in method development and validation.

Application

• Internal Standard for Quantitative Analysis: Used in GC-MS and LC-MS methods for the precise quantification of guaiacol and related phenolic compounds in complex matrices.
• Pharmaceutical Research: Facilitates pharmacokinetic and metabolic studies of drugs containing methoxyphenol moieties, enabling accurate tracking and measurement.
• Flavor and Fragrance Analysis: Critical for the accurate quantification of guaiacol, a key flavor component in smoke, whiskey, and vanilla, ensuring product consistency and quality.
• Environmental Monitoring: Employed in the analysis of environmental samples for phenolic pollutants derived from industrial processes or biomass burning.
• Biochemical Tracing: Serves as a tracer in biochemical and metabolic pathway research to study the fate of phenolic compounds.
• Method Development & Validation: Provides a critical reference point for developing and validating new analytical protocols, improving method robustness and compliance with regulatory guidelines.

Basic Information

Product Name	2-Methoxyphenol-3,4,5,6-D4,Od
CAS No.	20189-11-1
Molecular Formula	C7H4D4O2
Molecular Weight	128.16 g/mol (for D4 isotopologue)
Synonyms	Guaiacol-d4; 2-Methoxyphenol-d4; 1-Hydroxy-2-methoxybenzene-d4; o-Methoxyphenol-d4; Methylcatechol-d4 (ambiguous); Deuterated Guaiacol; [3,4,5,6-D4]-2-Methoxyphenol
EINECS	Contact for details

Quality Control

Our deuterated compounds are produced under strict quality control protocols to ensure high isotopic purity and chemical integrity. Each batch is characterized using advanced analytical techniques including NMR and Mass Spectrometry. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (atom % D), chemical purity, and analytical data is provided with every shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability and isotopic integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Isotopic Purity (Atom % D)	≥ 98% (by MS)
Chemical Purity (GC)	≥ 98%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.