Description

Difluorodimethylphosphorane CAS NO 20180-07-8 is a highly reactive organophosphorus compound characterized by its phosphorus-fluorine bonds. This compound serves as a versatile and powerful fluorinating and phosphorylating agent in advanced synthetic chemistry. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce fluorine atoms or dimethylphosphinyl groups into complex molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for the selective fluorination of active pharmaceutical ingredients (APIs) and advanced intermediates.
• Agrochemical Manufacturing: Used in the production of fluorinated pesticides and herbicides to enhance their biological activity and environmental stability.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized phosphine ligands and organometallic catalysts.
• Material Science Research: Employed in the development of novel fluorinated polymers and flame retardants.
• Organic Synthesis: A valuable tool for constructing P-C and P-F bonds in complex molecule assembly, including natural product synthesis.
• Electrolyte Additive Research: Investigated for use in lithium-ion battery electrolytes to improve performance and safety.

Basic Information

Product Name	Difluorodimethylphosphorane
CAS No.	20180-07-8
Molecular Formula	C₂H₆F₂P
Molecular Weight	114.04 g/mol
Synonyms	Dimethyldifluorophosphorane; Dimethylphosphorous Difluoride; (Difluoro)dimethylphosphorane; Phosphorane, difluorodimethyl-; Difluorodimethylphosphine; EINECS 243-600-8
EINECS	243-600-8

Quality Control

Our Difluorodimethylphosphorane is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including NMR (¹H, ¹⁹F, ³¹P), GC, and titration methods, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.