Description

6-[(S)-2,3-Dihydroxy-3-Methylbutyl]-7-Hydroxycoumarin is a specialized, optically active coumarin derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound matters as a high-value chiral building block and a potential precursor for developing novel bioactive molecules with specific stereochemistry. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, natural product synthesis, and as a reference standard for analytical purposes.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, particularly those requiring specific stereochemical configurations.
• Natural Product Synthesis: Used as a building block for the laboratory synthesis of complex natural products and coumarin-based analogs.
• Biochemical Research: Employed in studies investigating enzyme inhibition, receptor binding, or other biological activities associated with hydroxylated coumarin structures.
• Analytical Reference Standard: Utilized as a high-purity standard for quality control, method development, and identification in analytical laboratories (HPLC, LC-MS).
• Fine Chemical Synthesis: Acts as a precursor for the synthesis of more complex, functionalized organic molecules in specialized chemical manufacturing.

Basic Information

Product Name	6-[(S)-2,3-Dihydroxy-3-Methylbutyl]-7-Hydroxycoumarin
CAS No.	20126-72-1
Molecular Formula	C₁₅H₁₈O₅
Molecular Weight	278.30 g/mol
Synonyms	(S)-6-(2,3-Dihydroxy-3-methylbutyl)-7-hydroxy-2H-chromen-2-one; 7-Hydroxy-6-[(1S)-1,2-dihydroxy-1-methylpropyl]-2H-1-benzopyran-2-one; 6-[(1S)-1,2-Dihydroxy-1-methylpropyl]-7-hydroxycoumarin; (S)-Daphnetin derivative; (S)-7-Hydroxy-6-(2,3-dihydroxy-3-methylbutyl)coumarin; Light-sensitive coumarin derivative
EINECS	Contact for details

Quality Control

Our 6-[(S)-2,3-Dihydroxy-3-Methylbutyl]-7-Hydroxycoumarin is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and optical rotation measurement to confirm identity, purity, and chiral integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive (store away from light) and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Optical Rotation [α]₂₀D	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.