Description

[1S,4S,5S,(-)]-4-Methyl-1-(1-Methylethyl)Bicyclo[3.1.0]Hexane CAS NO 20126-20-9 is a high-purity, chiral bicyclic terpene derivative characterized by its unique strained ring structure and specific stereochemistry. This compound is valued as a critical chiral building block and intermediate in advanced organic synthesis, particularly for the development of complex molecules with defined three-dimensional architecture. It is essential for research and production in the pharmaceutical, agrochemical, and fine chemical industries, where precise stereochemical control is paramount for product efficacy and performance.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of novel therapeutic agents targeting the central nervous system and other specialized areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its specific stereochemistry can influence biological activity and environmental selectivity.
• Fine Chemical Manufacturing: Acts as a versatile building block for creating complex fragrances, flavors, and other high-value specialty chemicals that require specific stereoisomers.
• Catalyst and Ligand Development: Employed in the design and synthesis of novel chiral catalysts and ligands for asymmetric synthesis, enhancing the efficiency and selectivity of chemical transformations.
• Academic and Industrial R&D: A valuable tool for methodological studies in organic chemistry, enabling exploration of new reactions involving strained ring systems and stereoselective processes.
• Material Science Precursor: Investigated as a monomer or precursor for synthesizing specialized polymers and advanced materials with unique physical properties derived from its rigid bicyclic framework.

Basic Information

Product Name	[1S,4S,5S,(-)]-4-Methyl-1-(1-Methylethyl)Bicyclo[3.1.0]Hexane
CAS No.	20126-20-9
Molecular Formula	C10H18
Molecular Weight	138.25 g/mol
Synonyms	(-)-4-Methyl-1-(1-methylethyl)bicyclo[3.1.0]hexane; (1S,4S,5S)-4-Isopropyl-1-methylbicyclo[3.1.0]hexane; (-)-Sabinene (specific stereoisomer); 4-Isopropyl-1-methylbicyclo[3.1.0]hexane; Thuj-3-ene; Sabinene isomer; Bicyclo[3.1.0]hexane, 4-methyl-1-(1-methylethyl)-, (1S,4S,5S)-
EINECS	Contact for details

Quality Control

Our production of [1S,4S,5S,(-)]-4-Methyl-1-(1-Methylethyl)Bicyclo[3.1.0]Hexane adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure high chemical and isomeric purity suitable for sensitive synthetic applications. We provide detailed Certificates of Analysis (COA) with each shipment, documenting key parameters such as assay, enantiomeric excess, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area at controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and potential concentration changes. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to reference spectrum
Assay (GC)	≥ 97.0%
Enantiomeric Purity (Chiral GC/HPLC)	≥ 98.0% ee
Specific Rotation	Contact for details
Refractive Index	Contact for details
Density	~0.84 g/mL at 20°C
Related Substances (GC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.