Description

(R)-[1-(Chloromethyl)Propyl]Benzene is a chiral organic building block of significant interest in advanced chemical synthesis. This compound matters for its role as a key intermediate in the production of enantiomerically pure pharmaceuticals and agrochemicals, where stereochemical control is critical for efficacy and safety. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, fine chemical, and specialty materials sectors for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of active pharmaceutical ingredients (APIs) requiring specific (R)-configuration.
• Agrochemical Synthesis: Used in the research and production of enantiopure herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances where optical purity is essential.
• Material Science Research: Investigated as a monomer or building block for chiral polymers and advanced organic materials.

Basic Information

Product Name	(R)-[1-(Chloromethyl)Propyl]Benzene
CAS No.	20068-14-8
Molecular Formula	C10H13Cl
Molecular Weight	168.66 g/mol
Synonyms	(R)-1-Chloro-2-methyl-3-phenylpropane; (R)-1-Phenyl-2-methyl-3-chloropropane; (R)-α-Methylphenethyl chloride; (R)-β-Chloroisobutylbenzene; (R)-1-(Chloromethyl)-1-methyl-2-phenylethane; (R)-2-Methyl-3-phenylpropyl chloride; (R)-γ-Chloro-α-methyltoluene; Benzene, [(1R)-1-(chloromethyl)propyl]-
EINECS	Contact for details

Quality Control

Our (R)-[1-(Chloromethyl)Propyl]Benzene is produced under strict quality management systems to ensure batch-to-batch consistency and high optical purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing parameters such as chiral purity (enantiomeric excess), chemical purity, and identity confirmation. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture ingress and potential decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.