Description

Phenyl-β-D-Thioglucopyranoside is a specialized thioglycoside compound, serving as a crucial biochemical reagent and synthetic intermediate. Its primary value lies in its role as a substrate or inhibitor for various glycosidases and glycosyltransferases, enabling critical research in carbohydrate chemistry and enzymology. This product is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors, particularly those developing enzyme-based assays, metabolic pathway studies, and novel glycosylation inhibitors.

Application

• Enzyme Research & Assay Development: Acts as a chromogenic or fluorogenic substrate for β-glucosidase and related glycosidase enzymes in kinetic studies and high-throughput screening.
• Glycobiology Studies: Used as a mechanistic probe or inhibitor to investigate glycosyltransferase activity and carbohydrate-processing pathways.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of more complex thioglycosides and glycomimetics with potential therapeutic applications.
• Biochemical Standard: Employed as a reference standard in analytical methods (HPLC, LC-MS) for quality control and method validation in related compound analysis.
• Metabolic Pathway Analysis: Utilized in studies of carbohydrate metabolism and the role of specific glycosidase enzymes in cellular processes.

Basic Information

Product Name	Phenyl-β-D-Thioglucopyranoside
CAS No.	2936-70-1
Molecular Formula	C12H16O5S
Molecular Weight	272.32 g/mol
Synonyms	Phenyl 1-Thio-β-D-glucopyranoside; Phenyl β-D-Thioglucoside; 1-Thio-β-D-glucopyranosylbenzene; Phenyl-β-D-1-thioglucopyranoside; β-D-Glucopyranosyl phenyl sulfide; Phenyl thioglucoside; Phenyl-β-thioglucoside; Thioglucoside, phenyl-β-D-
EINECS	220-919-7

Quality Control

Our Phenyl-β-D-Thioglucopyranoside is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Specific Rotation [α]²⁰D	-85° to -95° (c=1 in H₂O)
Loss on Drying	≤ 1.0 %
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.