Description

Trifluorothioacetic Acid, 95 CAS NO 2925-25-9 is a specialized organosulfur and organofluorine compound characterized by its highly reactive thioester and trifluoromethyl groups. This chemical is a critical building block and reagent in advanced synthetic chemistry, enabling the efficient introduction of the S-CO-CF3 moiety into target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for applications ranging from novel drug synthesis to the creation of functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of complex molecules, particularly for introducing trifluoromethylthio groups which can enhance metabolic stability and lipophilicity of drug candidates.
• Agrochemical Synthesis: Used in the research and production of novel pesticides and herbicides, where the trifluoromethylthio group contributes to biological activity and environmental persistence profiles.
• Material Science Reagent: Employed in the modification of polymer backbones and surface functionalization to impart specific chemical resistance or surface energy properties.
• Organic Synthesis Building Block: Acts as a versatile reagent for acyl transfer reactions and as a precursor to other fluorinated thio compounds in academic and industrial R&D laboratories.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for catalysis, particularly in asymmetric synthesis and cross-coupling reactions.

Basic Information

Product Name	Trifluorothioacetic Acid, 95
CAS No.	2925-25-9
Molecular Formula	C2HF3OS
Molecular Weight	130.09 g/mol
Synonyms	Trifluoromethanethioic S-Acid; Trifluorothioacetic S-Acid; Perfluorothioacetic Acid; Thiotrifluoroacetic Acid; 2,2,2-Trifluoroethanethioic Acid; S-Trifluoroacetyl Thioate; TFTA; CF3C(O)SH
EINECS	220-879-6

Quality Control

Our Trifluorothioacetic Acid is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the specified 95% minimum purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications. We adhere to cGMP principles where applicable to support our customers in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its nature as a strong acid/organic solvent, it should be kept away from incompatible materials such as strong bases, oxidizing agents, and moisture. Containers must be kept tightly sealed when not in use to prevent volatilization and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.