Description

(E)-1-Phenyl-3-(2-Thienyl)-2-Propen-1-One is a high-purity organic compound belonging to the class of chalcone derivatives, characterized by its distinct α,β-unsaturated ketone structure. This compound serves as a versatile and critical synthetic intermediate in advanced organic synthesis and materials science research. It is primarily sought after by R&D laboratories and industrial chemists in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in therapeutic areas requiring heterocyclic scaffolds.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its bioactive chalcone core.
• Organic Electronics: Acts as a precursor for π-conjugated molecules in the research of organic semiconductors, OLEDs, and photovoltaic materials.
• Chemical Synthesis: Serves as a Michael acceptor or a dienophile in various cycloaddition and condensation reactions to construct complex polycyclic structures.
• Material Science: Investigated for use in nonlinear optical (NLO) materials and as a ligand or precursor in coordination chemistry.
• Flavor & Fragrance Intermediate: Potential use in the synthesis of complex aroma chemicals due to its specific ketone-thiophene structure.

Basic Information

Product Name	(E)-1-Phenyl-3-(2-Thienyl)-2-Propen-1-One
CAS No.	2910-81-8
Molecular Formula	C13H10OS
Molecular Weight	214.28 g/mol
Synonyms	(E)-3-(2-Thienyl)-1-phenyl-2-propen-1-one; 3-(2-Thienyl)-1-phenyl-2-propen-1-one; 2-Propen-1-one, 1-phenyl-3-(2-thienyl)-, (E)-; 3-(2-Thienyl)chalcone; (E)-3-(Thiophen-2-yl)-1-phenylprop-2-en-1-one; Chalcone, 3-(2-thienyl)-; 1-Phenyl-3-(2-thienyl)-2-propen-1-one
EINECS	220-835-7

Quality Control

Our (E)-1-Phenyl-3-(2-Thienyl)-2-Propen-1-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	88 - 92 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.