Description

2,2-Diphenyl-2-Ethoxyacetic Acid (1-Ethyl-4-Piperidyl) Ester Hydrochloride is a high-purity pharmaceutical intermediate and fine chemical building block. This compound is critical for research and development in medicinal chemistry, particularly for synthesizing novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical manufacturers, contract research organizations (CROs), and advanced chemical synthesis laboratories for its role in creating complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, particularly those targeting the central nervous system.
• Medicinal Chemistry Research: Used in R&D for structure-activity relationship (SAR) studies and lead optimization.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a precursor in multi-step synthesis routes for proprietary APIs.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals requiring a specific piperidine ester moiety.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Reference Standard: Used as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	2,2-Diphenyl-2-Ethoxyacetic Acid (1-Ethyl-4-Piperidyl) Ester Hydrochloride
CAS No.	2909-91-3
Molecular Formula	C23H29NO3·HCl
Molecular Weight	419.94 g/mol
Synonyms	1-Ethyl-4-piperidyl 2,2-diphenyl-2-ethoxyacetate hydrochloride; 2,2-Diphenyl-2-ethoxyacetic Acid 1-Ethyl-4-piperidinol Ester Hydrochloride; Etoxeridine Impurity; Etoxeridine Related Compound; Etoxeridine Hydrochloride Intermediate; NSC 112682; 1-Ethyl-4-piperidinol α-ethoxy-α,α-diphenylacetate hydrochloride
EINECS	220-829-5

Quality Control

Our 2,2-Diphenyl-2-Ethoxyacetic Acid (1-Ethyl-4-Piperidyl) Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) are provided with every shipment, detailing all specification results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.