Description

Ergoline-8-Carboxamide,9,10-Didehydro-6-Methyl-, (8A)- is a high-purity ergoline alkaloid derivative, a key structural motif in numerous pharmacologically active compounds. This intermediate is critical for ensuring the structural integrity and biological activity of complex synthetic targets in advanced research and development. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents, particularly within the central nervous system domain.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of complex ergot alkaloid derivatives and novel drug candidates.
• Neurological Research: Used in the development and study of compounds targeting serotonin and dopamine receptor systems.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Academic & Contract Research: Facilitates chemical biology studies and medicinal chemistry programs in university and CRO settings.
• Process Chemistry Development: Acts as a starting material or intermediate for scaling up synthetic routes under GMP or non-GMP conditions.

Basic Information

Product Name	Ergoline-8-Carboxamide,9,10-Didehydro-6-Methyl-, (8A)-
CAS No.	2889-26-1
Molecular Formula	C16H17N3O
Molecular Weight	267.33 g/mol
Synonyms	9,10-Didehydro-6-methyl-8α-ergoline-8-carboxamide; Lysergamide, 9,10-didehydro-6-methyl-, (8α)-; (8α)-9,10-Didehydro-6-methylergoline-8-carboxamide; 6-Methyl-9,10-didehydroergoline-8α-carboxamide; 8α-Isomer of Lysergamide; LAMPA; Contact for additional trade names.
EINECS	220-773-6

Quality Control

Our Ergoline-8-Carboxamide,9,10-Didehydro-6-Methyl-, (8A)- is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR), to ensure it meets exacting research and development standards. A detailed Certificate of Analysis (COA) with batch-specific data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.