Description

2-Bromo-5-Chlorothiophene is a halogenated thiophene derivative serving as a versatile and critical building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of pharmaceuticals and functional materials. Industrial and research chemists need it for applications ranging from active pharmaceutical ingredient (API) synthesis to the creation of novel agrochemicals and electronic materials.

Application

• Pharmaceutical Intermediates: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), especially those containing thiophene cores for therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides.
• Material Science: Serves as a precursor for conductive polymers, organic semiconductors, and other electronic materials.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research: A valuable reagent for method development, cross-coupling reactions (e.g., Suzuki, Stille), and exploring new heterocyclic chemistry.
• Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of complex organic dyes and pigments.

Basic Information

Product Name	2-Bromo-5-Chlorothiophene
CAS No.	2873-18-9
Molecular Formula	C4H2BrClS
Molecular Weight	197.48 g/mol
Synonyms	5-Chloro-2-bromothiophene; 2-Bromo-5-chlorothiophene; Thiophene, 2-bromo-5-chloro-; 2-Bromo-5-chloro-thiophene; NSC 403119; 2873-18-9; Bromochlorothiophene
EINECS	220-722-5

Quality Control

Our 2-Bromo-5-Chlorothiophene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is between 2°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.