Description

6-o-Methylcodeine is a semi-synthetic opioid alkaloid derived from codeine, distinguished by the methylation of the 6-hydroxy group. This structural modification is of significant interest in pharmaceutical research for studying structure-activity relationships and metabolic pathways of opioid compounds. It serves as a critical reference standard and intermediate for researchers and developers in the fine chemical and pharmaceutical industries.

Application

• Pharmaceutical Research & Development: Used as a key intermediate in the synthesis and study of novel opioid analgesics and their derivatives.
• Analytical Reference Standard: Serves as a high-purity certified standard for quality control and analytical method development in laboratories.
• Metabolic Studies: Employed in pharmacological research to investigate the metabolism, pharmacokinetics, and enzymatic O-methylation pathways of codeine-like compounds.
• Chemical Synthesis: Acts as a specialized building block for the preparation of more complex molecules for medicinal chemistry programs.
• Forensic Analysis: Utilized as a reference material in forensic toxicology for the identification and quantification of opioid substances.

Basic Information

Product Name	6-o-Methylcodeine
CAS No.	2859-16-7
Molecular Formula	C19H23NO3
Molecular Weight	313.39 g/mol
Synonyms	6-Methoxycodeine; 6-O-Methylcodeine; 3-Methoxy-17-methyl-9α,13α,14α-morphinan-6-ol; Codeine 6-methyl ether; 6-OMC
EINECS	220-685-3

Quality Control

Our 6-o-Methylcodeine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.