Description

3-(Diphenylphosphino)Propionic Acid is a versatile organophosphorus compound featuring both a phosphine group and a carboxylic acid functionality. This bifunctional structure makes it a valuable ligand and building block in advanced chemical synthesis, particularly for creating sophisticated catalysts and functional materials. It is essential for research and development in the pharmaceutical, agrochemical, and specialty chemical industries where precise molecular control is required.

Application

• Catalyst Ligand Synthesis: A key precursor for synthesizing chiral and achiral phosphine ligands used in cross-coupling reactions (e.g., Suzuki, Heck) and asymmetric hydrogenation.
• Pharmaceutical Intermediates: Serves as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs) and complex drug candidates.
• Polymer Modification: Used to incorporate phosphine groups into polymer backbones, imparting unique coordination properties for material science applications.
• Agrochemical Research: Employed in the development of novel pesticides and herbicides that require specific phosphine-based active sites.
• Surface Chemistry & Nanomaterials: Functionalizes nanoparticles and surfaces to create advanced catalytic systems or sensing platforms.
• Coordination Chemistry: Acts as a chelating agent for transition metals, forming stable complexes for study and application.

Basic Information

Product Name	3-(Diphenylphosphino)Propionic Acid
CAS No.	2848-01-3
Molecular Formula	C15H15O2P
Molecular Weight	258.25 g/mol
Synonyms	3-(Diphenylphosphino)propanoic Acid; Diphenylphosphinopropionic Acid; (3-Carboxypropyl)diphenylphosphine; 3-(Diphenylphosphanyl)propanoic Acid; NSC 163082; (3-Carboxyethyl)diphenylphosphine; γ-(Diphenylphosphino)butyric Acid (common misnomer); DPPPA
EINECS	220-653-9

Quality Control

Our 3-(Diphenylphosphino)Propionic Acid is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and titration methods, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its sensitivity to oxidation, containers should be kept sealed and purged after each use to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	118 - 122 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.