Description

Tetra(Ethylene Glycol) Dithiol CAS NO 2781-02-4 is a high-purity, bifunctional organic compound featuring terminal thiol groups linked by a tetraethylene glycol spacer. This molecular structure makes it a valuable versatile cross-linking agent and building block for synthesizing advanced materials with tailored properties. It is essential for researchers and manufacturers in the pharmaceutical, polymer, and nanotechnology sectors who require precise molecular control for creating functionalized surfaces, hydrogels, and conductive polymers.

Application

• Polymer Chemistry: As a cross-linker for synthesizing thiol-ene networks, elastomers, and hydrogels with controlled mechanical properties.
• Surface Modification & Self-Assembled Monolayers (SAMs): For functionalizing gold, silver, and other metal surfaces to create bio-compatible or conductive interfaces.
• Nanoparticle Capping & Stabilization: To provide a stable, functional shell around quantum dots and metallic nanoparticles, preventing aggregation.
• Bioconjugation & Drug Delivery: As a heterobifunctional linker for attaching peptides, proteins, or drugs to carrier systems via thiol-maleimide or thiol-haloacetyl chemistry.
• Adhesive & Sealant Formulations: Acting as a chain extender or curing agent in specialty epoxy and polyurethane systems.
• Conductive Polymer Synthesis: Serving as a monomer or dopant in the development of polymers for organic electronics.
• Chelating Agent Precursor: For the synthesis of ligands used in metal ion extraction and catalysis.

Basic Information

Product Name	Tetra(Ethylene Glycol) Dithiol
CAS No.	2781-02-4
Molecular Formula	C10H22O4S2
Molecular Weight	270.41 g/mol
Synonyms	2,2'-(Ethylenedioxy)diethanethiol; 3,6,9,12-Tetraoxatetradecane-1,14-dithiol; Tetraethylene glycol dithiol; Dithiol tetraethylene glycol; EG4 dithiol; 1,14-Dimercapto-3,6,9,12-tetraoxatetradecane; Thiol-PEG4-thiol; HS-PEG4-SH
EINECS	220-497-5

Quality Control

Our Tetra(Ethylene Glycol) Dithiol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets precise specifications for research and industrial use. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and maintain product integrity. Keep the container in a cool, dry, and well-ventilated place away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.