Description

5-Aminoindoline Dihydrochloride is a high-purity organic salt derivative of indoline, serving as a critical building block in advanced chemical synthesis. Its primary value lies in its dual amino functionality and dihydrochloride salt form, which enhances stability and solubility for precise pharmaceutical and agrochemical manufacturing processes. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to develop novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of serotonin receptor modulators, kinase inhibitors, and other bioactive nitrogen-containing heterocycles.
• Agrochemical Synthesis: Building block for developing new generation herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Organic Light-Emitting Diode (OLED) Materials: Used in the research and development of electron-transporting or host materials for display and lighting technologies.
• Dye and Pigment Manufacturing: Intermediate for producing advanced indoline-based dyes, pigments, and photographic chemicals.
• Academic and Industrial Research: Versatile starting material for methodological development in organic chemistry and medicinal chemistry programs.
• Ligand Synthesis for Catalysis: Used to prepare novel nitrogen-donor ligands for transition metal catalysis in fine chemical production.

Basic Information

Product Name	5-Aminoindoline Dihydrochloride
CAS No.	2759-14-0
Molecular Formula	C8H12Cl2N2
Molecular Weight	207.10 g/mol
Synonyms	5-Amino-2,3-dihydro-1H-indole dihydrochloride; 1H-Indole-5-amine, 2,3-dihydro-, hydrochloride (1:2); 2,3-Dihydro-1H-indol-5-amine dihydrochloride; Indoline-5-amine dihydrochloride; 5-Aminoindoline hydrochloride; 5-Aminoindoline, 2HCl; 5-Aminoindoline HCl
EINECS	Contact for details

Quality Control

Our 5-Aminoindoline Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identity confirmation via FT-IR and NMR. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with customer specifications and relevant industry guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.