Description

cis-Decahydroisoquinoline is a saturated heterocyclic amine of significant interest in advanced organic synthesis. This compound matters as a versatile chiral building block and intermediate for constructing complex nitrogen-containing molecular frameworks. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers for applications in medicinal chemistry, agrochemical development, and the synthesis of specialty catalysts and ligands.

Application

• Pharmaceutical Intermediate: A key chiral scaffold in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drugs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require specific stereochemistry.
• Catalyst & Ligand Preparation: Serves as a precursor for nitrogen-donor ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Research: Employed in academic and industrial R&D for studying stereoselective reactions and developing new synthetic methodologies.
• Fine Chemical Production: An intermediate for manufacturing dyes, pigments, and other high-value specialty chemicals.

Basic Information

Product Name	cis-Decahydroisoquinoline
CAS No.	2744-08-3
Molecular Formula	C9H17N
Molecular Weight	139.24 g/mol
Synonyms	cis-Perhydroisoquinoline; cis-Decahydro-2(1H)-isoquinolinone (tautomer); cis-Octahydro-1H-isoquinoline; 1,2,3,4,4a,5,6,7,8,8a-Decahydroisoquinoline (cis-); cis-1-Azadecalin; cis-2-Azabicyclo[4.3.0]nonane; Bicyclo[4.3.0]nonane, 2-aza-, cis-
EINECS	220-368-9

Quality Control

Our cis-Decahydroisoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity assessment and chiral purity verification, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Chiral Purity (Chiral GC/HPLC)	≥ 99.0% cis-isomer
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.