Description

Z-Trp-Ome, also known as Z-Tryptophan methyl ester, is a protected amino acid derivative of significant importance in synthetic organic and peptide chemistry. Its primary value lies in serving as a key chiral building block, where the Z (benzyloxycarbonyl) group provides orthogonal protection for the amine functionality during complex multi-step syntheses. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly for the development of novel peptides, peptidomimetics, and active pharmaceutical ingredients (APIs).

Application

• Peptide Synthesis: As a crucial intermediate for the solid-phase and solution-phase synthesis of peptides containing tryptophan residues.
• Pharmaceutical Research: Used in the research and development of therapeutic peptides, hormones, and enzyme inhibitors.
• Bioconjugation: Acts as a linker or spacer molecule in the design of antibody-drug conjugates (ADCs) and other bioconjugates.
• Chemical Biology: Employed in the synthesis of labeled peptides (e.g., fluorescent, isotopic) for proteomics and metabolic studies.
• Organic Synthesis: Serves as a versatile chiral synthon for the asymmetric synthesis of complex natural products and heterocyclic compounds.
• Catalyst & Ligand Development: Used to create novel chiral catalysts or ligands for asymmetric transformations.

Basic Information

Product Name	Z-Trp-Ome
CAS No.	2717-76-2
Molecular Formula	C20H20N2O4
Molecular Weight	352.39 g/mol
Synonyms	N-Carbobenzyloxy-L-tryptophan methyl ester; Nα-Z-L-Tryptophan methyl ester; (S)-Methyl 2-(((benzyloxy)carbonyl)amino)-3-(1H-indol-3-yl)propanoate; Z-L-Tryptophan-OMe; Z-L-Trp-OMe; CBZ-L-Tryptophan methyl ester; Benzyloxycarbonyl-L-tryptophan methyl ester; Nα-CBZ-L-Tryptophan methyl ester
EINECS	Contact for details

Quality Control

Our Z-Trp-Ome CAS NO 2717-76-2 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high chemical purity and chiral integrity, meeting the stringent requirements of research and cGMP manufacturing. Key parameters such as assay (HPLC), enantiomeric excess (Chiral HPLC), and identity (IR, NMR) are verified. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Melting Point	Contact for details
Specific Rotation	Contact for details
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.