Description

Methyl (Triphenylphosphoranylidene)Acetate CAS NO 2605-67-6 is a high-value Wittig reagent, specifically a stabilized ylide, essential for the synthesis of α,β-unsaturated esters. Its primary value lies in enabling the efficient and stereoselective construction of carbon-carbon double bonds, a fundamental transformation in organic synthesis. This reagent is indispensable for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries, where it is used to build complex molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: Key building block for creating α,β-unsaturated ester motifs prevalent in active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Production: Used in the synthesis of complex molecules for crop protection agents and pesticides.
• Fine Chemical & Specialty Chemical Manufacturing: Employed in the production of flavors, fragrances, and performance chemicals requiring specific alkene geometries.
• Material Science Research: Facilitates the synthesis of monomers and precursors for polymers and advanced organic materials.
• Academic & R&D Laboratories: A staple reagent for methodological development and exploratory synthesis in organic chemistry.
• Process Chemistry: Valued for its reliability and defined reactivity in scaling up synthetic routes from lab to pilot plant.

Basic Information

Product Name	Methyl (Triphenylphosphoranylidene)Acetate
CAS No.	2605-67-6
Molecular Formula	C21H19O2P
Molecular Weight	334.35 g/mol
Synonyms	(Carbomethoxymethylene)triphenylphosphorane; Methyl 2-(triphenylphosphoranylidene)acetate; Methyl (triphenylphosphoranylidene)ethanoate; Triphenylphosphoranylidene acetic acid methyl ester; Wittig reagent - Methyl (triphenylphosphoranylidene)acetate; Methyl P,P,P-triphenylphosphoranylideneacetate; Acetic acid, 2-(triphenylphosphoranylidene)-, methyl ester
EINECS	220-025-2

Quality Control

Our Methyl (Triphenylphosphoranylidene)Acetate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including NMR, HPLC, and titration, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	168 - 172 °C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.