Description

7-[2-[[2-(3,4-Dihydroxyphenyl)-2-Hydroxyethyl]Amino]Ethyl]-3,7-Dihydro-1,3-Dimethyl-1H-Purine-2,6-Dione Monohydrochloride is a high-purity pharmaceutical intermediate and research chemical. This compound is valued for its role as a key synthetic precursor in the development of cardiovascular and neurological therapeutics, particularly those targeting adrenergic and adenosine receptor pathways. It is essential for pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and advanced fine chemical synthesis.

Application

• Pharmaceutical Intermediate: Critical precursor in the synthesis of complex active pharmaceutical ingredients (APIs) for cardiovascular drugs.
• Biochemical Research: Used as a reference standard and building block in studies of adenosine receptor agonists and related neurological pathways.
• Contract Synthesis: Supplied to CMOs and CDMOs for custom synthesis projects requiring high-purity, specialized purine derivatives.
• Academic Research: Utilized in university and institutional labs for medicinal chemistry and pharmacology research programs.
• Process Development: Serves as a starting material for process chemistry optimization and scale-up studies in pilot plants.

Basic Information

Product Name	7-[2-[[2-(3,4-Dihydroxyphenyl)-2-Hydroxyethyl]Amino]Ethyl]-3,7-Dihydro-1,3-Dimethyl-1H-Purine-2,6-Dione Monohydrochloride
CAS No.	2572-61-4
Molecular Formula	C₁₇H₂₄ClN₅O₅
Molecular Weight	413.85 g/mol
Synonyms	1H-Purine-2,6-dione, 7-[2-[[2-(3,4-dihydroxyphenyl)-2-hydroxyethyl]amino]ethyl]-3,7-dihydro-1,3-dimethyl-, monohydrochloride; Dyphylline Impurity D Hydrochloride; 7-(2-((2-(3,4-Dihydroxyphenyl)-2-hydroxyethyl)amino)ethyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione hydrochloride; Dyphylline Related Compound D HCl; 1,3-Dimethyl-7-[2-[[2-(3,4-dihydroxyphenyl)-2-hydroxyethyl]amino]ethyl]xanthine Hydrochloride; Arofylline Impurity D Hydrochloride; Diprophylline Impurity D HCl
EINECS	Contact for details

Quality Control

Our production of this compound adheres to strict quality management systems, ensuring batch-to-batch consistency for research and cGMP manufacturing. Quality is verified through comprehensive analytical methods including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, consider under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.