Description

Cyclopropane, 2-Bromo-1-Ethynyl-1-Methyl- (7Ci,8Ci) is a highly functionalized cyclopropane derivative, serving as a versatile and valuable building block in advanced organic synthesis. Its unique structure, featuring a bromine atom, an ethynyl group, and a methyl group on a strained three-membered ring, makes it a critical precursor for constructing complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries, where it is used to introduce cyclopropane motifs and enable novel chemical transformations.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the cyclopropane ring can enhance biological activity and stability.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials with tailored properties.
• Organic Synthesis Building Block: Employed in [3+2] cycloadditions, cross-coupling reactions (e.g., Sonogashira, Suzuki), and ring-opening/expansion reactions to create complex, polycyclic structures.
• Ligand and Catalyst Development: Utilized as a precursor for synthesizing novel chiral ligands and organometallic catalysts for asymmetric synthesis.
• Academic and R&D Laboratories: A fundamental reagent for methodological studies and exploring new reaction pathways in synthetic organic chemistry.

Basic Information

Product Name	Cyclopropane, 2-Bromo-1-Ethynyl-1-Methyl- (7Ci,8Ci)
CAS No.	2568-76-5
Molecular Formula	C6H5Br
Molecular Weight	157.01 g/mol
Synonyms	2-Bromo-1-ethynyl-1-methylcyclopropane; 1-Methyl-1-ethynyl-2-bromocyclopropane; 2-Bromo-1-methyl-1-(ethynyl)cyclopropane; Bromo(ethynyl)methylcyclopropane; (2-Bromocyclopropyl)methylacetylene
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch of Cyclopropane, 2-Bromo-1-Ethynyl-1-Methyl- is analyzed using advanced techniques including GC, HPLC, and NMR to verify identity, purity, and consistency. We adhere to strict internal quality management protocols. Certificates of Analysis (COA) are available upon request and provide full traceability and detailed analytical results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place, away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is 2-8°C (refrigerated) for long-term stability. Allow the container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.