Description

Anisole-2,4,6-D3 is a deuterated analog of anisole, specifically labeled at the 2, 4, and 6 positions of the aromatic ring. This compound is a crucial stable isotope-labeled standard, providing unmatched precision for analytical quantification and metabolic pathway tracing in research. It is essential for scientists and quality control professionals in the pharmaceutical, agrochemical, and advanced materials sectors who require high-fidelity internal standards for mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy.

Application

• Internal Standard for Mass Spectrometry (MS): Serves as a critical quantitative reference in LC-MS and GC-MS analysis of anisole and its derivatives, ensuring accurate measurement in complex matrices.
• Metabolic Pathway Tracing: Used in pharmaceutical and biochemical research to track the fate of anisole-containing compounds in biological systems using NMR or MS.
• NMR Spectroscopy Solvent & Reagent: Acts as a deuterated solvent or a probing reagent in NMR studies to elucidate molecular structure and dynamics without signal interference.
• Pharmaceutical Impurity Profiling: Enables the precise identification and quantification of process-related impurities and degradation products in drug substances and products.
• Agrochemical Research: Utilized in environmental fate studies and residue analysis of anisole-based pesticides and herbicides.
• Organic Synthesis Intermediate: Employed in the synthesis of more complex deuterated compounds for research in material science and medicinal chemistry.
• Quality Control & Method Development: Fundamental for developing and validating robust analytical methods in compliance with ICH and GMP guidelines.

Basic Information

Product Name	Anisole-2,4,6-D3
CAS No.	2567-25-1
Molecular Formula	C7H5D3O
Molecular Weight	111.16 g/mol
Synonyms	Deuterated Anisole (2,4,6-D3); Methoxybenzene-2,4,6-D3; (2,4,6-Trideuterio)anisole; Anisole-d3; Methyl Phenyl Ether-2,4,6-D3; 1-Methoxy-2,4,6-trideuteriobenzene; Benzene, 1-methoxy-2,4,6-d3-
EINECS	Contact for details

Quality Control

Every batch of Anisole-2,4,6-D3 is manufactured and analyzed under strict quality systems. We guarantee high chemical and isotopic purity, verified by advanced analytical techniques including NMR, MS, and HPLC. A comprehensive Certificate of Analysis (COA) detailing assay, isotopic enrichment, and impurity profile is provided with each shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Isotopic Enrichment (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.