Description

3-Fluorothiophenol is a versatile fluorinated aromatic thiol building block, essential for introducing sulfur and fluorine functionalities into complex molecular architectures. Its unique structure makes it a critical intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs) where specific electronic and steric properties are required. This compound is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for applications ranging from ligand synthesis to polymer modification.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands in transition metal catalysis, useful in cross-coupling reactions.
• Material Science: Employed in the modification of polymers and resins to impart specific chemical resistance or surface properties.
• Organic Synthesis Reagent: Acts as a nucleophile in substitution reactions or as a protecting group agent in multi-step synthetic routes.
• Chemical Research: Fundamental reagent in academic and industrial R&D for exploring new fluorinated heterocyclic compounds.

Basic Information

Product Name	3-Fluorothiophenol
CAS No.	2557-77-9
Molecular Formula	C6H5FS
Molecular Weight	128.17 g/mol
Synonyms	3-Fluorobenzenethiol; m-Fluorothiophenol; 3-Fluorophenyl mercaptan; 1-Fluoro-3-mercaptobenzene; Benzenethiol, 3-fluoro-; 3-Fluoro-thiophenol; m-Fluorobenzenethiol; 3-Fluorothiophenol (m-Fluorothiophenol)
EINECS	219-875-3

Quality Control

Our 3-Fluorothiophenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen) to prevent oxidation. Keep away from heat, sparks, open flames, and strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.