Description

α-Cyclopropyl-4-Fluoro-α-Methylbenzyl Alcohol is a versatile chiral alcohol intermediate featuring a cyclopropyl and a fluorinated aromatic ring. This compound is valued for its unique steric and electronic properties, which are critical for modulating the biological activity and physicochemical characteristics of target molecules. It is primarily sought after by pharmaceutical R&D and fine chemical synthesis teams for the development of advanced active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorinated benzyl moiety enhances bioavailability and stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers and liquid crystals due to its rigid, fluorinated structure.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including new fluorination and cross-coupling reactions.

Basic Information

Product Name	α-Cyclopropyl-4-Fluoro-α-Methylbenzyl Alcohol
CAS No.	2542-09-8
Molecular Formula	C12H15FO
Molecular Weight	194.25 g/mol
Synonyms	(±)-1-Cyclopropyl-1-(4-fluorophenyl)ethanol; 1-(4-Fluorophenyl)-1-cyclopropylethanol; α-Cyclopropyl-4-fluoro-α-methylbenzyl alcohol; 1-Cyclopropyl-1-(4-fluorophenyl)ethan-1-ol; 4-Fluoro-α-(1-cyclopropylethyl)benzyl alcohol; (4-Fluorophenyl)(cyclopropyl)methyl methyl alcohol; Benzenemethanol, 4-fluoro-α-(1-cyclopropylethyl)-
EINECS	Contact for details

Quality Control

Our α-Cyclopropyl-4-Fluoro-α-Methylbenzyl Alcohol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess (where applicable), and identity confirmation via NMR and IR spectroscopy. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.