Description

5-Iodo-1-Pentyne is a versatile halogenated alkyne building block essential for advanced organic synthesis. Its unique structure, featuring both an iodine atom and a terminal alkyne group, makes it a critical reagent for cross-coupling reactions and click chemistry. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries to construct complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates via Sonogashira and other palladium-catalyzed cross-coupling reactions.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides by introducing the pentyne moiety into target molecules.
• Material Science & Polymer Chemistry: Serves as a monomer or functionalization agent in the creation of specialty polymers, dendrimers, and functionalized surfaces.
• Click Chemistry: The terminal alkyne group readily participates in Huisgen 1,3-dipolar cycloadditions (e.g., with azides) for bioconjugation and labeling applications.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for catalysis and organometallic complexes.
• Organic Synthesis Building Block: Fundamental for constructing carbon-carbon bonds and introducing functionalized alkyl chains into more complex organic molecules.

Basic Information

Product Name	5-Iodo-1-Pentyne
CAS No.	2468-55-5
Molecular Formula	C5H7I
Molecular Weight	194.01 g/mol
Synonyms	1-Pentyne, 5-iodo-; 5-Iodopentyne; 5-Iodo-1-pentyne; 1-Iodo-4-pentyne; 4-Pentyn-1-yl iodide; Iodopentyne
EINECS	219-567-1

Quality Control

Our 5-Iodo-1-Pentyne is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles. We adhere to relevant industry standards to support your R&D and scale-up needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.