Description

2-Mercapto-1-Phenylethanone is a versatile sulfur-containing aromatic ketone with the CAS number 2462-02-4. This compound serves as a critical building block and intermediate in advanced organic synthesis, valued for its reactive thiol and carbonyl functionalities. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel compounds and fine-tuning material properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those containing thioether or heterocyclic structures.
• Agrochemical Synthesis: Used in the development of novel pesticides, herbicides, and fungicides where the thiol group introduces specific biological activity.
• Ligand and Catalyst Preparation: Acts as a starting material for synthesizing specialized ligands used in transition metal catalysis and coordination chemistry.
• Polymer Modification: Employed as a chain transfer agent or functional monomer to introduce thiol groups into polymer backbones, altering material properties.
• Flavor and Fragrance Industry: Intermediate for the production of certain sulfur-containing aroma compounds, contributing to savory or roasted notes.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new organic reactions and synthesizing complex molecular architectures.

Basic Information

Product Name	2-Mercapto-1-Phenylethanone
CAS No.	2462-02-4
Molecular Formula	C8H8OS
Molecular Weight	152.21 g/mol
Synonyms	Phenacyl Mercaptan; α-Mercaptoacetophenone; 2-Thiol-1-phenylethanone; 2-Sulfanyl-1-phenylethanone; 2-Mercaptoacetophenone; Thioglycolophenone; (Oxoethyl)benzene thiol; Mercaptomethyl phenyl ketone
EINECS	219-554-8

Quality Control

Our 2-Mercapto-1-Phenylethanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming identity, assay, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.