Description

8-Hydroxycoumarin is a versatile organic compound belonging to the coumarin family, serving as a key synthetic intermediate and active moiety in various industrial and research applications. Its significance lies in its bifunctional structure, featuring both a phenolic hydroxyl group and a lactone ring, which makes it a valuable precursor for synthesizing more complex molecules, including pharmaceuticals, agrochemicals, and fluorescent dyes. This product is essential for manufacturers and R&D laboratories in the pharmaceutical, chemical synthesis, and material science sectors seeking a reliable, high-purity building block.

Application

• Pharmaceutical Intermediate: A crucial starting material for the synthesis of anticoagulant drugs (e.g., warfarin analogs), antimicrobial agents, and other bioactive coumarin derivatives.
• Agrochemical Synthesis: Used in the production of pesticides and herbicides, where the coumarin scaffold contributes to biological activity.
• Fluorescent Probe & Dye Manufacturing: Acts as a core structure for developing fluorescent chelating agents and optical brighteners due to its inherent luminescent properties.
• Organic Synthesis Building Block: Employed in various organic reactions, including etherification, esterification, and metal complex formation, for creating specialty chemicals.
• Research & Development: Utilized in academic and industrial R&D for studying enzyme inhibition, antioxidant activity, and material properties.
• Cosmetic Ingredient Precursor: Serves as an intermediate in the synthesis of certain UV absorbers and fragrance components.

Basic Information

Product Name	8-Hydroxycoumarin
CAS No.	2442-31-1
Molecular Formula	C9H6O3
Molecular Weight	162.14 g/mol
Synonyms	8-Hydroxy-2H-chromen-2-one; 8-Hydroxy-2H-1-benzopyran-2-one; 8-Hydroxy-2-oxo-2H-chromene; 8-Hydroxycoumarin; NSC 38287; 8-HC; β-Hydroxycoumarin; Umbelliferone (Note: Umbelliferone typically refers to 7-Hydroxycoumarin, but 8-Hydroxycoumarin is a positional isomer)
EINECS	219-478-5

Quality Control

Our 8-Hydroxycoumarin is produced under a stringent quality management system to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as assay, identity, and impurity profiles. While we offer standard technical and research grades, our processes can be adapted to meet specific customer requirements, including higher purity specifications for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	230°C - 235°C
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.