Description

Trifluoro-Sulfanylidene-Phosphorane is a highly reactive organophosphorus compound characterized by its unique trifluoromethyl and sulfanylidene functional groups. This specialized reagent is valued for its role as a key building block in advanced synthetic chemistry, enabling the introduction of phosphorus and sulfur motifs into complex molecular architectures. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting neurological and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, pesticides, and plant growth regulators requiring specific phosphorus-sulfur chemistry.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized phosphine-based ligands used in transition metal catalysis for fine chemical production.
• Material Science Research: Employed in the development of novel polymers, flame retardants, and electronic materials where phosphorus incorporation is desired.
• Fluorochemical Building Block: Utilized in organic synthesis to introduce the reactive -CF3 group into target molecules, a valuable modification in medicinal chemistry.
• Academic & Industrial R&D: A key reagent for methodological development in organic synthesis and exploratory chemistry within corporate and university laboratories.

Basic Information

Product Name	Trifluoro-Sulfanylidene-Phosphorane
CAS No.	2404-52-6
Molecular Formula	F3PS
Molecular Weight	120.03 g/mol
Synonyms	Phosphorous Trifluoride Sulfide; Thiophosphoryl Fluoride; Phosphorothioic Trifluoride; Trifluorothiophosphorane; Phosphorothioic Fluoride (PF3S); Sulfur Phosphorus Trifluoride; Pentafluorosulfanylphosphorane (common misnomer); PSF3
EINECS	219-300-0

Quality Control

Every batch of Trifluoro-Sulfanylidene-Phosphorane is produced and analyzed under strict quality management protocols. We ensure compliance with relevant industry standards for high-purity chemical intermediates. Comprehensive testing, including assay by GC and impurity profiling, is performed to guarantee consistency and reliability for your synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and highly volatile nature, this material must be stored in a cool, dry, and well-ventilated place. For long-term stability, storage under an inert atmosphere (argon or nitrogen) in a sealed vessel is strongly recommended. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid / gas
Identification (IR)	Conforms to reference spectrum
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Major Impurity (GC)	PF5 / PF3 ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.