Description

2-(4-Bromophenyl)-1,1,1,3,3,3-Hexafluoro-2-Propanol is a high-purity fluorinated aromatic alcohol building block, valued for its unique combination of a bromo-substituted phenyl ring and a highly fluorinated propanol group. This structure makes it a critical intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs) where enhanced lipophilicity, metabolic stability, and electronic properties are required. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials industries.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluorine atoms contribute to improved biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, enhancing thermal stability and optical properties.
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart unique characteristics such as oil and water repellency, chemical resistance, and low surface energy.
• Catalyst & Ligand Preparation: Utilized in the synthesis of sophisticated ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Advanced Material Research: Employed in academic and industrial R&D for creating novel fluorinated compounds with tailored properties for high-tech applications.

Basic Information

Item	Detail
Product Name	2-(4-Bromophenyl)-1,1,1,3,3,3-Hexafluoro-2-Propanol
CAS No.	2402-72-4
Molecular Formula	C9H5BrF6O
Molecular Weight	323.03 g/mol
Synonyms	4-Bromo-α,α-bis(trifluoromethyl)benzyl alcohol; 1-(4-Bromophenyl)-2,2,2-trifluoro-1-(trifluoromethyl)ethanol; Hexafluoro-2-(4-bromophenyl)-2-propanol; 2-(p-Bromophenyl)-1,1,1,3,3,3-hexafluoro-2-propanol; α,α-Bis(trifluoromethyl)-4-bromobenzyl alcohol; p-Bromo-α,α-bis(trifluoromethyl)benzyl alcohol; (4-Bromophenyl)hexafluoroisopropanol
EINECS	Contact for details

Quality Control

Our 2-(4-Bromophenyl)-1,1,1,3,3,3-Hexafluoro-2-Propanol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.