Description

4-tert-Amylthiophenol is a specialized organosulfur compound featuring a tert-amyl group attached to a thiophenol moiety. This structure makes it a valuable intermediate and reagent in advanced organic synthesis, particularly where steric hindrance and specific electronic properties are required. It is primarily utilized by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries for applications such as ligand synthesis, polymer modification, and as a building block for complex molecules.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring sterically hindered thiophenol derivatives.
• Agrochemical Synthesis: Used in the production of pesticides, herbicides, and fungicides where the tert-amylthio group can influence biological activity and stability.
• Polymer Chemistry: Acts as a chain transfer agent, modifier, or cross-linking agent in the production of specialty polymers and resins to alter physical properties.
• Ligand and Catalyst Preparation: Employed in the development of novel ligands for metal-catalyzed reactions, including palladium-catalyzed cross-couplings.
• Material Science Research: Utilized in surface modification and the creation of self-assembled monolayers (SAMs) for advanced material coatings.
• Organic Synthesis Reagent: Functions as a nucleophile or a precursor for introducing the tert-amylthio functional group into more complex organic frameworks.

Basic Information

Product Name	4-tert-Amylthiophenol
CAS No.	2396-69-2
Molecular Formula	C11H16S
Molecular Weight	180.31 g/mol
Synonyms	p-tert-Amylthiophenol; 4-(1,1-Dimethylpropyl)thiophenol; 4-(tert-Pentyl)thiophenol; 4-(2-Methylbutan-2-yl)benzenethiol; 4-(1,1-Dimethylpropyl)benzenethiol; p-(1,1-Dimethylpropyl)thiophenol; Benzenethiol, 4-(1,1-dimethylpropyl)-
EINECS	219-254-6

Quality Control

Our 4-tert-Amylthiophenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C/59-77°F). Due to its property of being easily oxidized, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, open flames, and strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.