Description

4-tert-Butylthiophenol is a specialized organosulfur compound featuring a tert-butyl group attached to a thiophenol moiety. This structure makes it a valuable intermediate and ligand in advanced chemical synthesis, particularly where steric hindrance and electron-donating properties are required. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and polymer industries for applications ranging from catalyst development to the synthesis of high-performance materials.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring thioether linkages or sterically hindered phenolic groups.
• Catalyst & Ligand Synthesis: Used to prepare ligands for transition metal catalysts in cross-coupling and other organometallic reactions.
• Polymer Chemistry: Acts as a chain-transfer agent, modifier, or stabilizer in the production of specialty polymers and resins to impart specific properties.
• Agrochemical Synthesis: Employed as an intermediate in the manufacture of certain herbicides, fungicides, and pesticides.
• Material Science Research: Utilized in the development of novel organic electronic materials, liquid crystals, and self-assembled monolayers (SAMs).
• Chemical Synthesis Reagent: Functions as a nucleophile or a protecting group precursor in complex organic synthesis.

Basic Information

Product Name	4-tert-Butylthiophenol
CAS No.	2396-68-1
Molecular Formula	C10H14S
Molecular Weight	166.28 g/mol
Synonyms	p-tert-Butylthiophenol; 4-(1,1-Dimethylethyl)benzenethiol; 4-tert-Butylbenzenethiol; 4-(tert-Butyl)thiophenol; 4-tert-Butylphenyl mercaptan; p-tert-Butylbenzenethiol; 1-tert-Butyl-4-mercaptobenzene; Thioguaiacol tert-butyl ether (related)
EINECS	219-252-5

Quality Control

Our 4-tert-Butylthiophenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as assay, impurity profile, and physical properties. Our quality commitment ensures the material meets the stringent requirements for research and industrial synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider maintaining under an inert atmosphere (e.g., nitrogen or argon) to preserve stability and purity. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.