Description

1-Fluoro-3-(Pentafluoroethyl)Benzene is a high-value fluorinated aromatic building block characterized by its unique combination of a fluorine substituent and a pentafluoroethyl group. This structure imparts exceptional chemical stability, lipophilicity, and electron-withdrawing properties, making it a critical intermediate for advanced synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for creating novel active ingredients, as well as by specialty chemical manufacturers developing advanced materials and liquid crystals.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of active pharmaceutical ingredients (APIs), particularly for introducing fluorinated motifs to enhance metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorinated groups can improve biological activity and environmental persistence profiles.
• Liquid Crystal Materials: Acts as a core component or side-chain modifier in the synthesis of fluorinated liquid crystals for high-performance displays (LCDs).
• Organic Electronics: Employed in the development of organic semiconductors and dielectric materials due to its electron-deficient aromatic system.
• Specialty Polymer Modifier: Incorporated into polymer chains to enhance chemical resistance, thermal stability, and surface properties of high-performance plastics and coatings.
• Chemical Research & Development: A versatile reagent for exploring new fluorination reactions and constructing complex molecular architectures in academic and industrial R&D settings.

Basic Information

Product Name	1-Fluoro-3-(Pentafluoroethyl)Benzene
CAS No.	2396-10-3
Molecular Formula	C8H4F6
Molecular Weight	214.11 g/mol
Synonyms	3-(Pentafluoroethyl)fluorobenzene; 1-Fluoro-3-(1,1,2,2,2-pentafluoroethyl)benzene; m-(Pentafluoroethyl)fluorobenzene; 3-Fluoropentafluoroethylbenzene; Benzene, 1-fluoro-3-(pentafluoroethyl)-; α,α,α,2,2-Pentafluoroethyl-3-fluorobenzene
EINECS	Contact for details

Quality Control

Our 1-Fluoro-3-(Pentafluoroethyl)Benzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, guaranteeing traceability and compliance with your research or production specifications. Custom purity grades and analytical packages are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flames. The container should be kept upright and sealed when not in use to prevent moisture ingress and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	≤ 2.0% total
Density (20°C)	~1.55 g/mL
Refractive Index (n20D)	~1.39

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.