Description

(E)-1-Bromo-2-Fluoroethene is a halogenated alkene building block of significant interest in advanced organic synthesis. Its core value lies in its ability to introduce both bromine and fluorine atoms in a stereodefined manner, enabling precise molecular construction. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty materials sectors who require high-purity intermediates for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of fluorinated drug candidates, particularly in antiviral and anticancer research.
• Agrochemical Synthesis: Used in constructing novel, biologically active molecules for crop protection agents.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers and fluorinated materials.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic substitutions to create complex, fluorinated organic structures.
• Ligand and Catalyst Development: Useful for synthesizing novel fluorinated ligands for catalysis and molecular recognition.
• Fluorine-18 Radiochemistry: Potential precursor for the synthesis of PET (Positron Emission Tomography) imaging agents, though typically handled in specialized facilities.

Basic Information

Product Name	(E)-1-Bromo-2-Fluoroethene
CAS No.	2366-32-7
Molecular Formula	C2H2BrF
Molecular Weight	124.94 g/mol
Synonyms	trans-1-Bromo-2-fluoroethene; (E)-1-Bromo-2-fluoroethylene; 1-Bromo-2-fluoroethene (E)-; Bromofluoroethene; 2-Fluoro-1-bromoethene; (E)-Bromofluoroethylene; trans-Bromofluoroethene; 2366-32-7
EINECS	Contact for details

Quality Control

We supply (E)-1-Bromo-2-Fluoroethene in high-purity grades suitable for research and process development. Every batch undergoes rigorous analytical testing, including GC, GC-MS, and NMR, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. Our quality management system supports compliance with cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place, away from heat sources and incompatible materials such as strong bases and oxidizing agents. Due to its high volatility, containers must be kept tightly sealed and under appropriate conditions (typically 2-8°C or as specified on the label) to maintain stability and prevent loss.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0% (Area %)
Isomeric Purity ((E)-isomer)	≥ 98.0% (by GC or NMR)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.