Description

3-Aminopiperidine-2,6-Dione is a high-purity, heterocyclic organic compound featuring both amine and imide functional groups, making it a versatile and valuable building block in advanced synthesis. Its unique structure is critical for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of active pharmaceutical ingredients (APIs), particularly for oncology and central nervous system (CNS) targeted therapies.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a crucial linker component in the design of novel PROTAC molecules for targeted protein degradation.
• Peptidomimetic Chemistry: Used to introduce constrained, heterocyclic scaffolds into peptide analogs to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Employed as a building block for developing new herbicides, fungicides, and plant growth regulators with novel modes of action.
• Ligand and Catalyst Development: Utilized in the synthesis of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Academic and Industrial R&D: A fundamental reagent for methodological studies in organic synthesis and medicinal chemistry exploration.

Basic Information

Product Name	3-Aminopiperidine-2,6-Dione
CAS No.	2353-44-8
Molecular Formula	C5H8N2O2
Molecular Weight	128.13 g/mol
Synonyms	3-Amino-2,6-piperidinedione; 3-Aminoglutarimide; 3-Aminopiperidine-2,6-dione hydrochloride (salt form); Aminoglutarimide; 2,6-Dioxo-3-aminopiperidine; 3-Amino-piperidine-2,6-dione; NSC 163501
EINECS	Contact for details

Quality Control

Our 3-Aminopiperidine-2,6-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and cGMP manufacturing. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, assay, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.