Description

(Hydroxymethyl)Triphenylphosphonium Tetrafluoroborate is a versatile organophosphorus salt, specifically a phosphonium ylide precursor, widely recognized for its role in the Wittig olefination reaction. Its primary value lies in its ability to facilitate the synthesis of terminal alkenes from carbonyl compounds, making it a critical reagent for constructing carbon-carbon double bonds with high stereoselectivity. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity building blocks for complex molecule synthesis.

Application

• Wittig Reaction Reagent: A key precursor for generating methylenetriphenylphosphorane, used for the homologation of aldehydes and ketones to terminal alkenes.
• Pharmaceutical Intermediate Synthesis: Employed in the production of active pharmaceutical ingredients (APIs) and complex organic molecules requiring olefin functionalities.
• Agrochemical Manufacturing: Used in the synthesis of pesticide and herbicide intermediates that incorporate alkene groups.
• Material Science Research: Applied in the development of organic semiconductors, liquid crystals, and polymers where defined alkene linkages are crucial.
• Fine Chemical Production: Serves as a specialized reagent for the custom synthesis of flavors, fragrances, and other high-value chemicals.
• Academic & Industrial R&D: A staple reagent in organic chemistry laboratories for method development and exploratory synthesis.

Basic Information

Product Name	(Hydroxymethyl)Triphenylphosphonium Tetrafluoroborate
CAS No.	2340-49-0
Molecular Formula	C19H20BF4OP
Molecular Weight	382.14 g/mol
Synonyms	Hydroxymethyltriphenylphosphonium Tetrafluoroborate; (Hydroxymethyl)triphenylphosphonium Boron Tetrafluoride; Triphenyl(hydroxymethyl)phosphonium Tetrafluoroborate; Formylmethylenetriphenylphosphorane Salt; Wittig Reagent Precursor; Phosphonium Salt, (hydroxymethyl)triphenyl-, tetrafluoroborate(1-)
EINECS	219-055-6

Quality Control

Our (Hydroxymethyl)Triphenylphosphonium Tetrafluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high chemical purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 1.0 %
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.