Description

3-Methoxy-6,17-Dimethylmorphinan-6α-Ol is a high-purity, specialized morphinan derivative of significant interest in advanced pharmaceutical research and development. Its unique structural framework makes it a critical intermediate for synthesizing novel therapeutic agents targeting the central nervous system. This compound is essential for research laboratories and pharmaceutical companies focused on developing new analgesics, antitussives, or other neuroactive pharmaceuticals, where precise chemical building blocks are paramount.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of new opioid receptor modulators and other neuropharmacological agents.
• Reference Standard: Used as a high-purity analytical standard in quality control (QC) and research & development (R&D) laboratories for method development and compound identification.
• Medicinal Chemistry Research: A valuable scaffold for structure-activity relationship (SAR) studies aimed at discovering new molecules with potential analgesic or central nervous system (CNS) activity.
• Biochemical Research: Employed in studies investigating the binding and functional characteristics of morphinan-based compounds at various biological targets.
• Process Chemistry Development: Used in the scale-up and optimization of synthetic routes for complex active pharmaceutical ingredients (APIs) within the morphinan class.

Basic Information

Product Name	3-Methoxy-6,17-Dimethylmorphinan-6α-Ol
CAS No.	2246-06-2
Molecular Formula	C19H27NO2
Molecular Weight	301.43 g/mol
Synonyms	6α-Hydroxy-3-methoxy-6,17-dimethylmorphinan; 3-Methoxy-6,17-dimethylmorphinan-6α-ol; 6α-Hydroxy-3-methoxy-N-methylmorphinan; 3-Methoxy-6-methylmorphinan-6-ol; Levomethorphan intermediate; Morphinan-6α-ol, 3-methoxy-6,17-dimethyl-; (5α,6α)-3-Methoxy-6,17-dimethylmorphinan-6-ol
EINECS	Contact for details

Quality Control

Our 3-Methoxy-6,17-Dimethylmorphinan-6α-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and tests for residual solvents and related substances. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure full traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.