Description

1,4-Dibromo-2-Butyne is a versatile brominated alkyne building block with significant utility in advanced organic synthesis. Its high reactivity, stemming from the presence of both bromine atoms and a triple bond, makes it a critical intermediate for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those requiring alkyne or bromoalkyne functional groups for further coupling reactions (e.g., Sonogashira, Click chemistry).
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its molecular structure can be incorporated to modulate biological activity.
• Material Science: Acts as a monomer or cross-linking agent in the development of specialty polymers, resins, and advanced materials with tailored properties.
• Organic Synthesis Building Block: Employed in laboratory-scale and industrial organic synthesis for cyclization reactions, chain extensions, and as a source of electrophilic bromine.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands and organometallic complexes for catalytic applications.
• Life Sciences Research: Functions as a biochemical probe or labeling reagent in bioconjugation strategies due to its reactive alkyne moiety.

Basic Information

Product Name	1,4-Dibromo-2-Butyne
CAS No.	2219-66-1
Molecular Formula	C4H4Br2
Molecular Weight	227.88 g/mol
Synonyms	1,4-Dibromobut-2-yne; 2-Butyne, 1,4-dibromo-; Dibromobutylene; 1,4-Dibromo-2-butyne; But-2-yne-1,4-dibromide; 1,4-Dibromo-but-2-in (German); 1,4-ジブロモ-2-ブチン (Japanese)
EINECS	218-746-9

Quality Control

Our 1,4-Dibromo-2-Butyne is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing including GC, HPLC, and NMR to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality parameters. Our commitment to reliable supply and traceability meets the demanding standards of research and industrial-scale applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is 2-8°C for long-term stability. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~2.0 g/mL
Refractive Index (n20D)	~1.56

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.