Description

1-o-Palmitoyl-2-o-Stearoyl-3-o-Oleoylglycerol is a well-defined, high-purity structured triglyceride (TAG) with a specific positional arrangement of fatty acid chains. This precise molecular configuration is critical for applications requiring controlled lipid behavior, such as in advanced lipid-based drug delivery systems and specialized nutritional formulations. It is an essential intermediate and reference standard for researchers and manufacturers in the pharmaceutical, nutraceutical, and specialty chemical industries seeking consistent and reproducible lipid performance.

Application

• Pharmaceutical Excipient: As a key lipid component in the development of solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs) for enhanced drug solubility and targeted delivery.
• Reference Standard: For analytical method development, calibration, and quality control in chromatography (HPLC, GC) to identify and quantify complex lipid mixtures.
• Biochemical Research: Used in studies of lipid metabolism, enzyme specificity (e.g., lipases), and membrane biophysics due to its defined structure.
• Specialty Nutrition: A model structured fat for researching and formulating specialized medical nutrition and infant formula to mimic specific fat absorption profiles.
• Cosmetic Ingredient: Employed in high-end skincare formulations as an emollient and carrier for active ingredients, providing stable texture and skin barrier benefits.
• Chemical Synthesis: Serves as a versatile building block or starting material for the synthesis of more complex lipids, phospholipids, and other ester derivatives.

Basic Information

Product Name	1-o-Palmitoyl-2-o-Stearoyl-3-o-Oleoylglycerol
CAS No.	2190-28-5
Molecular Formula	C55H104O6
Molecular Weight	861.42 g/mol
Synonyms	1-Palmitoyl-2-stearoyl-3-oleoyl-sn-glycerol; PSG; POS (Palmitic-Stearic-Oleic Glyceride); Glycerol 1-palmitate 2-stearate 3-oleate; sn-Glycerol-1-palmitate-2-stearate-3-oleate; TAG (16:0/18:0/18:1); Triglyceride POS; Structured Lipid POS
EINECS	218-577-8

Quality Control

Our 1-o-Palmitoyl-2-o-Stearoyl-3-o-Oleoylglycerol is produced and tested under a strict quality management system. Each batch is analyzed to ensure high chemical purity and structural integrity, with specifications tailored to meet the rigorous demands of pharmaceutical and research applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by HPLC), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) to minimize oxidation. For long-term storage, keep desiccated at -20°C. Allow the container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white waxy solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (TLC)	Single spot
Acid Value	≤ 1.0 mg KOH/g
Peroxide Value	≤ 5.0 meq/kg
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.