Description

Methyl 4-(Triphenylphosphonio)Crotonate Bromide is a specialized organophosphorus salt, widely recognized as a versatile Wittig reagent and a key intermediate in organic synthesis. This compound is essential for facilitating the stereoselective formation of α,β-unsaturated esters, a critical transformation in the production of complex molecules. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and advanced materials sectors for constructing carbon-carbon double bonds with high precision.

Application

• Pharmaceutical Intermediate: A crucial reagent for synthesizing active pharmaceutical ingredients (APIs), particularly those containing conjugated ester functionalities.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents and herbicides that require specific alkene geometries.
• Fine Chemical Manufacturing: Serves as a key building block for fragrances, flavors, and specialty chemicals where controlled olefination is required.
• Material Science Research: Employed in the development of novel polymers and organic electronic materials with tailored properties.
• Academic & Industrial R&D: A fundamental tool in organic chemistry laboratories for method development and the synthesis of complex natural products.
• Process Chemistry: Applied in scalable routes for the commercial production of fine chemicals, offering reliable reactivity.

Basic Information

Product Name	Methyl 4-(Triphenylphosphonio)Crotonate Bromide
CAS No.	2181-98-8
Molecular Formula	C23H22BrO2P
Molecular Weight	441.30 g/mol
Synonyms	Methyl (E)-4-(Triphenylphosphoranylidene)-2-butenoate Bromide; Methyl 4-(Triphenylphosphoranylidene)crotonate Bromide; (Carbomethoxyethylene)triphenylphosphorane Bromide; Methyl (2E)-4-(triphenyl-λ5-phosphanylidene)but-2-enoate Bromide; Wittig Reagent - Methyl Crotonate Derivative; TPPMCB; 2181-98-8
EINECS	Contact for details

Quality Control

Our Methyl 4-(Triphenylphosphonio)Crotonate Bromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and elemental analysis, to ensure high purity and consistent performance as a synthesis reagent. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and assay is provided with every shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect reactivity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.