Description

4-tert-Butyl-Thiazole-2-Thiol is a specialized sulfur and nitrogen-containing heterocyclic compound with the CAS number 2180-05-4. This chemical serves as a versatile intermediate and building block, valued for its unique thiol and thiazole functionalities which enable diverse chemical modifications. It is primarily sought by research and development chemists, as well as process engineers, in the pharmaceutical, agrochemical, and specialty chemical industries for synthesizing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting neurological or metabolic pathways.
• Agrochemical Synthesis: Used in the research and development of new pesticides, herbicides, and fungicides, leveraging its heterocyclic core.
• Ligand and Catalyst Precursor: The thiol group makes it a useful precursor for creating metal-chelating ligands in catalytic systems.
• Polymer Modification: Employed to introduce thiazole moieties into polymer chains, potentially altering material properties like UV stability or conductivity.
• Chemical Research (R&D): A valuable reagent for exploring new organic reactions and synthesizing complex heterocyclic libraries for screening.
• Flavor & Fragrance Intermediate: May serve as a precursor for certain sulfur-containing compounds used in high-value aroma chemicals.

Basic Information

Product Name	4-tert-Butyl-Thiazole-2-Thiol
CAS No.	2180-05-4
Molecular Formula	C7H11NS2
Molecular Weight	173.30 g/mol
Synonyms	2-Mercapto-4-tert-butylthiazole; 4-(1,1-Dimethylethyl)-2-thiazolethiol; 4-tert-Butyl-2-mercaptothiazole; 4-tert-Butyl-2-thiazolinethione; 2-Thiazolethiol, 4-(1,1-dimethylethyl)-; 4-tert-Butylthiazole-2-thiol; 4-tert-Butyl-1,3-thiazole-2-thiol; NSC 403697
EINECS	218-548-8

Quality Control

Our 4-tert-Butyl-Thiazole-2-Thiol is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets precise customer specifications. A detailed Certificate of Analysis (COA) documenting all test results is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.