Description

2-Bromo-5-(Methylsulfonyl)Thiophene is a high-value, multi-functional heterocyclic building block characterized by its bromine and methylsulfonyl substituents. This compound matters for its role as a critical intermediate in the synthesis of complex organic molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the thiophene core for bioactivity.
• Material Science Research: Acts as a monomer or building block for creating conjugated polymers and organic electronic materials like OLEDs and organic semiconductors.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form complex biaryl structures.
• Ligand and Catalyst Development: Utilized in the design of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying biological pathways and protein interactions.

Basic Information

Product Name	2-Bromo-5-(Methylsulfonyl)Thiophene
CAS No.	2160-61-4
Molecular Formula	C5H5BrO2S2
Molecular Weight	241.12 g/mol
Synonyms	2-Bromo-5-methylsulfonylthiophene; 5-(Methylsulfonyl)-2-bromothiophene; Thiophene, 2-bromo-5-(methylsulfonyl)-; 2-Bromo-5-methanesulfonylthiophene; 2-Bromothiophene-5-sulfonic acid methyl ester; 2160-61-4; 2-Bromo-5-(methylsulfonyl)thiophene
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-(Methylsulfonyl)Thiophene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.