Description

1-(5-Bromo-4-Nitro-2-Thienyl)Ethan-1-One is a high-purity, specialized heterocyclic building block containing bromo and nitro functional groups on a thiophene core. This compound is critical for advanced organic synthesis, particularly in the development of complex molecules for pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and material science industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in the development of molecules with thiophene-based pharmacophores.
• Agrochemical Research: Used in the creation of new herbicides, fungicides, and insecticides, leveraging its reactive halogen and nitro groups for further derivatization.
• Material Science: Serves as a precursor for organic semiconductors, conductive polymers, and non-linear optical (NLO) materials due to the electron-accepting nitro group and the π-conjugated thiophene system.
• Chemical Synthesis: Acts as a versatile building block in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic aromatic substitution, enabling the construction of complex heterocyclic architectures.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized dyes and pigments where the thiophene ring contributes to color and stability properties.

Basic Information

Product Name	1-(5-Bromo-4-Nitro-2-Thienyl)Ethan-1-One
CAS No.	2160-55-6
Molecular Formula	C6H4BrNO3S
Molecular Weight	250.07 g/mol
Synonyms	5-Bromo-4-nitro-2-acetylthiophene; 2-Acetyl-5-bromo-4-nitrothiophene; 1-(5-Bromo-4-nitro-2-thienyl)ethanone; Ethanone, 1-(5-bromo-4-nitro-2-thienyl)-; 5-Bromo-4-nitrothiophene-2-yl methyl ketone; 2-Acetyl-4-nitro-5-bromothiophene
EINECS	Contact for details

Quality Control

Our production of 1-(5-Bromo-4-Nitro-2-Thienyl)Ethan-1-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR, IR) to confirm identity and quantify purity. A comprehensive Certificate of Analysis (COA) detailing assay, impurity profile, and physical characteristics is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.