Description

Ethyl 3-Hydroxy-5-Phenylthiophene-2-Carboxylate is a high-purity organic building block and pharmaceutical intermediate of significant commercial importance. This compound is valued for its versatile heterocyclic structure, which serves as a key precursor in the synthesis of more complex molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in therapeutic areas targeting central nervous system (CNS) disorders and inflammation.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its thiophene core for bioactive molecule design.
• Organic Electronic Materials: Serves as a precursor for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs) and organic photovoltaics (OPVs).
• Chemical Research & Development: Employed as a versatile synthon in academic and industrial R&D for exploring new heterocyclic chemistry and reaction pathways.
• Dye and Pigment Intermediate: Acts as a starting material for the production of specialized dyes and pigments due to its chromophoric thiophene structure.
• Ligand Synthesis for Catalysis: Utilized to create complex ligands for transition metal catalysts used in asymmetric synthesis and cross-coupling reactions.

Basic Information

Product Name	Ethyl 3-Hydroxy-5-Phenylthiophene-2-Carboxylate
CAS No.	2158-86-3
Molecular Formula	C13H12O3S
Molecular Weight	248.30 g/mol
Synonyms	Ethyl 3-hydroxy-5-phenyl-2-thiophenecarboxylate; 3-Hydroxy-5-phenylthiophene-2-carboxylic acid ethyl ester; 5-Phenyl-3-hydroxythiophene-2-carboxylic acid ethyl ester; 2-Thiophenecarboxylic acid, 3-hydroxy-5-phenyl-, ethyl ester; Ethyl 5-phenyl-3-hydroxythiophene-2-carboxylate; 3-Hydroxy-5-phenylthiophene-2-carboxylate ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 3-Hydroxy-5-Phenylthiophene-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.