Description

4-Hydroxy-2-Methyl-3-Thiophenecarboxylic Acid Ethyl Ester is a high-purity, functionalized thiophene derivative that serves as a critical building block in advanced organic synthesis. Its unique heterocyclic structure, featuring both hydroxyl and ester functionalities, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to develop new active ingredients or functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents, such as herbicides and fungicides, leveraging its heterocyclic core.
• Material Science Research: Serves as a precursor for organic electronic materials, including conductive polymers and semiconductors, due to the electron-rich thiophene ring.
• Chemical Research & Development: Employed as a versatile building block in organic synthesis for constructing complex heterocyclic compounds and fine chemicals.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized dyes and pigments where the thiophene moiety contributes to color and stability properties.

Basic Information

Product Name	4-Hydroxy-2-Methyl-3-Thiophenecarboxylic Acid Ethyl Ester
CAS No.	2158-82-9
Molecular Formula	C8H10O3S
Molecular Weight	186.23 g/mol
Synonyms	Ethyl 4-Hydroxy-2-methylthiophene-3-carboxylate; 4-Hydroxy-2-methyl-3-thiophenecarboxylic acid ethyl ester; 3-Thiophenecarboxylic acid, 4-hydroxy-2-methyl-, ethyl ester; 2-Methyl-4-hydroxythiophene-3-carboxylic acid ethyl ester; Ethyl 2-methyl-4-hydroxythiophene-3-carboxylate; 2158-82-9; NSC 163063
EINECS	218-475-9

Quality Control

Our 4-Hydroxy-2-Methyl-3-Thiophenecarboxylic Acid Ethyl Ester is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent chemical identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. The container must be kept tightly closed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.