Description

1-Methyl-3-(Piperidin-4-Yl)-1H-Benzo[D]Imidazol-2(3H)-One Hydrochloride is a high-purity, pharmaceutically relevant organic salt, primarily valued as a critical intermediate in the synthesis of advanced active pharmaceutical ingredients (APIs). Its core value proposition lies in enabling the development of novel therapeutic agents, particularly in the central nervous system (CNS) and oncology research fields. This compound is essential for B2B buyers in pharmaceutical R&D, contract manufacturing organizations (CMOs), and fine chemical suppliers who require a reliable source of high-quality building blocks for complex molecular synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting neurological disorders.
• Active Pharmaceutical Ingredient (API) Development: Used in research and process development for new therapeutic agents.
• Chemical Synthesis Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies.
• Preclinical & Clinical Trial Material Production: Supplied under controlled conditions for the manufacture of compounds used in non-clinical and clinical studies.
• Contract Manufacturing: Supplied to CMOs and CDMOs for scale-up and commercial production of proprietary pharmaceuticals.
• Reference Standard: Used as an analytical standard for quality control and regulatory submissions.

Basic Information

Product Name	1-Methyl-3-(Piperidin-4-Yl)-1H-Benzo[D]Imidazol-2(3H)-One Hydrochloride
CAS No.	2147-85-5
Molecular Formula	C14H18N3O·HCl
Molecular Weight	281.78 g/mol (Free base: 244.31 g/mol)
Synonyms	1-Methyl-3-(4-piperidinyl)-1H-benzimidazol-2(3H)-one hydrochloride; 1-Methyl-3-piperidin-4-yl-1,3-dihydro-2H-benzimidazol-2-one hydrochloride; 2(3H)-Benzimidazolone, 1-methyl-3-(4-piperidinyl)-, monohydrochloride; UNII-9F1JX6KQ1H; 9F1JX6KQ1H; 1-Methyl-3-(piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one HCl; 2147-85-5 (CAS)
EINECS	Contact for details

Quality Control

Our 1-Methyl-3-(Piperidin-4-Yl)-1H-Benzo[D]Imidazol-2(3H)-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for pharmaceutical research and development. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring traceability, consistency, and reliability for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%; Any single impurity ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.