Description

1,2,4-Trimethyl-5-Iodobenzene is a high-purity, multi-substituted aromatic building block of significant interest in advanced organic synthesis. Its value lies in the strategic placement of iodine and methyl groups, which enables selective functionalization for creating complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-quality intermediates for coupling reactions and ligand synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) via cross-coupling reactions such as Suzuki-Miyaura or Buchwald-Hartwig amination.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the iodine moiety allows for the introduction of heterocyclic or other functional groups.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in homogeneous catalysis and organometallic chemistry.
• Material Science Research: Employed in the creation of organic electronic materials, liquid crystals, and advanced polymers where its structure can influence material properties.
• Chemical Research & Development: A versatile building block in academic and industrial R&D for exploring new synthetic pathways and creating compound libraries.

Basic Information

Product Name	1,2,4-Trimethyl-5-Iodobenzene
CAS No.	2100-23-4
Molecular Formula	C9H11I
Molecular Weight	246.09 g/mol
Synonyms	5-Iodo-1,2,4-trimethylbenzene; 2,4,5-Trimethyliodobenzene; 1-Iodo-2,4,5-trimethylbenzene; 5-Iodopseudocumene; Pseudocumene, 5-iodo-; Benzene, 1,2,4-trimethyl-5-iodo-; 2100-23-4
EINECS	218-267-8

Quality Control

Our 1,2,4-Trimethyl-5-Iodobenzene is manufactured under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality systems are designed to meet the stringent requirements of research and development as well as scale-up production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.