Description

3-[[(2S)-1-Methylpyrrolidine 1-Oxide]-2α-Yl]Pyridine 1-Oxide is a specialized heterocyclic compound featuring a nitroxyl radical structure, making it a valuable intermediate and research chemical. This compound is critical for applications requiring stable free radicals, particularly in advanced material science and pharmaceutical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and polymer industries for use as a spin label, catalyst component, or building block for complex molecular architectures.

Application

• Spin Labeling Agent: Used in Electron Paramagnetic Resonance (EPR) spectroscopy to study the structure and dynamics of biomolecules, polymers, and materials.
• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting neurological disorders.
• Polymerization Catalyst/Modifier: Acts as a stable nitroxide mediator in controlled radical polymerization processes, such as Nitroxide-Mediated Polymerization (NMP), for producing polymers with precise architectures.
• Agrochemical Research: Employed in the development of new crop protection agents due to its unique heterocyclic framework.
• Material Science: Incorporated into organic electronic materials and magnetic materials as a radical source or dopant to modify electronic properties.
• Analytical Chemistry Standard: Utilized as a standard or reference compound in various chromatographic and spectroscopic analytical methods.

Basic Information

Product Name	3-[[(2S)-1-Methylpyrrolidine 1-Oxide]-2α-Yl]Pyridine 1-Oxide
CAS No.	2055-29-0
Molecular Formula	C11H14N2O2
Molecular Weight	206.24 g/mol
Synonyms	(2S)-1-Methyl-2-(3-pyridinyl)pyrrolidine 1-Oxide; 3-[(2S)-1-Methyl-1-oxido-2-pyrrolidinyl]pyridine 1-Oxide; 3-(1-Methyl-1-oxido-2-pyrrolidinyl)pyridine 1-Oxide (stereoisomer); (S)-3-(1-Methylpyrrolidin-1-ium-1-yl)pyridine 1-Oxide; Nitroxyl Radical Derivative of Pyridine; PROXYL-type Nitroxide Derivative; 3-Pyridyl PROXYL; Stable Free Radical Intermediate
EINECS	Contact for details

Quality Control

Every batch of 3-[[(2S)-1-Methylpyrrolidine 1-Oxide]-2α-Yl]Pyridine 1-Oxide is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, chiral purity, and impurity profiles. Our quality protocols are designed to meet the stringent requirements of research and development as well as cGMP standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.