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Borane-Triphenylphosphine Complex CAS NO 2049-55-0


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CAS No.:2049-55-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Borane-Triphenylphosphine Complex is a versatile and widely used borane adduct, serving as a stable source of borane (BH₃) for selective reduction and hydroboration reactions. Its primary value lies in its ability to act as a mild and controllable reducing agent, offering chemists a safer and more convenient alternative to gaseous diborane. This complex is essential for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries, where it is employed in the synthesis of active pharmaceutical ingredients (APIs), chiral intermediates, and other high-value specialty molecules.

Application

  • Selective Reduction of Functional Groups: Used for the chemoselective reduction of aldehydes, ketones, and carboxylic acids to their corresponding alcohols.
  • Hydroboration of Alkenes and Alkynes: Acts as a key reagent in hydroboration-oxidation sequences to synthesize primary and secondary alcohols with anti-Markovnikov regioselectivity.
  • Pharmaceutical Intermediate Synthesis: A critical reagent in multi-step syntheses for creating chiral centers and complex molecular scaffolds in drug discovery and development.
  • Asymmetric Synthesis: Employed in conjunction with chiral auxiliaries or catalysts to produce enantiomerically enriched compounds.
  • Polymer Chemistry: Used as an initiator or modifying agent in the synthesis and functionalization of polymers.
  • Agrochemical Manufacturing: Applied in the production of advanced pesticide and herbicide intermediates.
  • Academic and R&D Laboratories: A staple reagent for methodological development and exploratory organic synthesis.

Basic Information

Product Name Borane-Triphenylphosphine Complex
CAS No. 2049-55-0
Molecular Formula C₁₈H₁₈BP
Molecular Weight 276.12 g/mol
Synonyms Borane–triphenylphosphine; Borane-Triphenylphosphine Adduct; Triphenylphosphine-Borane Complex; BH₃•PPh₃; Borane-Phosphine Complex; Borane Triphenylphosphorus; Phenylphosphine borane (1:1); Boron hydride-triphenylphosphine (1:1)
EINECS 218-079-7

Quality Control

Our Borane-Triphenylphosphine Complex is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged operations to maintain optimal reactivity and purity.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (Titration) ≥ 97.0%
Melting Point 180 - 185 °C
Loss on Drying ≤ 0.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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