Description

5-(Bromomethyl)-3-Phenylisoxazole is a versatile brominated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the construction of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the life sciences sector for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the isoxazole moiety imparts specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials and photoactive compounds due to its conjugated phenylisoxazole structure.
• Chemical Biology Probes: Utilized to create tagged molecules or activity-based probes for studying biological pathways and enzyme functions.
• Cross-Coupling Reactions: Acts as an electrophilic partner in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.

Basic Information

Product Name	5-(Bromomethyl)-3-Phenylisoxazole
CAS No.	2039-50-1
Molecular Formula	C10H8BrNO
Molecular Weight	238.08 g/mol
Synonyms	3-Phenyl-5-(bromomethyl)isoxazole; 5-Bromomethyl-3-phenylisoxazole; 3-Phenyl-5-bromomethylisoxazole; 5-(Bromomethyl)-3-phenyl-1,2-oxazole; Isoxazole, 5-(bromomethyl)-3-phenyl-; 2039-50-1; 5-Bromomethyl-3-phenyl-1,2-oxazole
EINECS	Contact for details

Quality Control

Our 5-(Bromomethyl)-3-Phenylisoxazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing batch-specific results are available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.