Description

Bamifylline CAS NO 2016-63-9 is a xanthine derivative and a potent phosphodiesterase (PDE) inhibitor. This compound is valued for its research applications in studying cellular signaling pathways, particularly those involving cyclic nucleotides. It is primarily utilized by pharmaceutical research organizations and academic institutions investigating respiratory and cardiovascular pharmacology.

Application

• Pharmaceutical Research & Development: A key reference standard and active compound for studying PDE inhibition mechanisms.
• Biochemical Assay Development: Used in in vitro assays to investigate the role of specific PDE isoenzymes in disease models.
• Academic Research: Employed in university and institutional labs for fundamental research on bronchodilation, vasodilation, and anti-inflammatory effects.
• Preclinical Studies: Serves as a tool compound in animal models for respiratory conditions like asthma and chronic obstructive pulmonary disease (COPD).
• Chemical Intermediate: Can be used in the synthesis of more complex pharmaceutical molecules targeting PDE activity.
• Reference Material: Provides a high-purity standard for analytical method development and validation in quality control laboratories.

Basic Information

Product Name	Bamifylline
CAS No.	2016-63-9
Molecular Formula	C19H23N5O2
Molecular Weight	353.42 g/mol
Synonyms	Bamifylline; 8-Benzyl-7-[2-(ethylamino)ethyl]-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione; BAX 308 Z; AC 3810; Benzyltheophylline ethylaminoethyl; 1H-Purine-2,6-dione, 3,7-dihydro-8-(phenylmethyl)-7-[2-(ethylamino)ethyl]-1,3-dimethyl-
EINECS	Contact for details

Quality Control

Our Bamifylline is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by spectroscopic methods (IR, NMR), and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Certificates are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.