Description

Isoprenaline Sulphate is a synthetic catecholamine and a potent non-selective β-adrenergic receptor agonist. This compound is of significant importance in pharmaceutical research and development, serving as a key reference standard and active pharmaceutical ingredient (API) intermediate. It is primarily needed by manufacturers and research institutions in the pharmaceutical, biotechnology, and life science sectors for applications in cardiovascular research, analytical method development, and quality control.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification, assay, and impurity profiling of related drug substances and products in pharmacopeial testing (e.g., USP, EP).
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a critical synthetic precursor in the manufacturing of finished dosage forms, such as inhalation solutions for bronchospasm.
• Biochemical Research: Employed in cardiovascular and pulmonary research to study β-adrenergic receptor signaling, bronchodilation, and cardiac stimulation mechanisms.
• Analytical Chemistry: Utilized as an analytical standard in High-Performance Liquid Chromatography (HPLC), mass spectrometry, and other techniques for method validation and calibration.
• Quality Control & Assurance: Essential for in-house quality control laboratories to ensure the identity, strength, purity, and quality of raw materials and finished products.

Basic Information

Product Name	Isoprenaline Sulphate
CAS No.	299-95-6
Molecular Formula	C22H30N2O10S
Molecular Weight	520.55 g/mol
Synonyms	Isoproterenol Sulphate; Isoprenaline Sulfate; Isoproterenol Sulfate; 1-(3,4-Dihydroxyphenyl)-2-isopropylaminoethanol Sulphate; 3,4-Dihydroxy-α-[(isopropylamino)methyl]benzyl Alcohol Sulphate; Aleudrin Sulphate; Aludrin Sulphate; Isonorin Sulphate; Norisodrine Sulphate
EINECS	206-081-5

Quality Control

Our Isoprenaline Sulphate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for identity, purity, and potency. We provide full traceability and support current Good Manufacturing Practice (cGMP) principles for pharmaceutical intermediates. A detailed Certificate of Analysis (COA) is available for every lot, confirming compliance with relevant standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.